Drugs and alcohol can change the brain to foster compulsive use and abuse.
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River Phoenix knew he was experiencing an overdose from a deadly cocktail of cocaine and heroin the night of his death at Johnny Depp's Los Angeles nightclub claims a friend of the actor who was there that fateful evening.
As the world prepares to mark 20-years since the death of Phoenix at the tragically young age of 23, his friend and former Helonious Monster front-man Bob Forrest has revealed the harrowing last moments before the actor collapsed.
Unsteady on his feet and ghostly white, Forrest recalls how Phoenix turned to him on Halloween, 1993 and pleaded, 'I don't feel so good.
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